During pregnancy, your body makes more of the hormone progesterone. This hormone may relax the valve between your stomach and esophagus. Most of the time, the valve stays closed to keep acid in. Pantoprazole (Protonix) is used as a short-term treatment for gastroesophageal reflux disease (GERD), by blocking the production of acid made in the stomach. Advice and warnings for the use of Pantoprazole during pregnancy. FDA Pregnancy Category B - No proven risk in humans Several published observational studies suggest that proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine. Unfortunately our full catalog may not be displayed in your state. If you contact our Customer Support by one of the methods below, we will be able to assist you in locating the product you are looking for. Learn about Protonix (Pantoprazole) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Pantoprazole (Protonix) is used to treat erosive esophagitis and other conditions involving excess stomach acid. Includes pantoprazole side effects, interactions and indications. Guidance, Compliance & Regulatory Information. Looking for FDA Guidance, Compliance, & Regulatory Information? Web page provides quick links to a variety of topics. Pantoprazole, first sold under the brand name Protonix, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome. It may also. DailyMed Announcements. Posted: December 19, 2017. Drug Listing Certification. The U.S. Food and Drug Administration is reminding the pharmaceutical industry of the December 31, 2017, deadline to update or certify their drug listings with FDA.